Genetic Factors and Polypeptide Chain Subclasses of Human Immunoglobulin G Detected in Chimpanzee Serums

Abstract

The Gm and Inv genetic factors, characteristic antigens of human immunoglobulin G, were detected in chimpanzee serums. All animals tested were Gm(a+, x—, b^l—, b²—, b³+, b⁴+). Polymorphism was demonstrated for factors Gm(c), Inv(l), and Inv(b). Three of the subclasses of heavy polypeptide chains and both types of light polypeptide chains that are present in human immunoglobulin G were identified in chimpanzee serums.