THE RENAL CLEARANCES OF IODIDE AND L-DIIODOTYROSINE MEASURED SIMULTANEOUSLY*
Open Access
- 1 May 1959
- journal article
- research article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 38 (5), 784-787
- https://doi.org/10.1172/jci103860
Abstract
Simultaneous determinations of the renal clearance of I131-labeled diiodotyrosine and I133-labeled iodide have been performed. Differential measurement of the 2 isotopes was found to be technically feasible. The apparent renal clearance of diiodotyrosine is lower than the true clearance because of intrarenal deiodination of diiodotyrosine.Keywords
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