An Effect of Dietary Sulfate on Selenium Poisoning in the Rat

Abstract
Dietary sulfate was shown to restore partially the growth of selenized rats receiving a purified diet with selenium added as selenite or as selenate. Sulfate levels of 0.29, 0.58 and 0.87% as sodium or as potassium salts progressively relieved the growth inhibition due to selenium. Alleviations of greater than 40% were observed. Sulfate, however, did not substantially prevent liver degeneration due to selenium.