This article is an overview of Michel Callon's contribution to the reformulation of economic sociology and anthropology. It contextualizes Callon's concepts within science and technology studies, and indicates the main lines of influence on his thinking about economic processes. Callon's work also opens up a number of debates and challenges to current perspectives within economic sociology. Finally, the article considers the way in which Callon's perspective reconfigures both the relation of politics and economics, and the nature of politics itself.