Health and insurance interests have substantially increased their contributions to members of Congress in response to the debate over national health care. During the 21 months from January 1, 1993, through September 30, 1994, campaign contributions from the health and insurance industries reached $37.9 million, a 51 percent increase over the same time period in the last election cycle. Health- and insurance-related large donor contributions ($200 or more) increased at the fastest rate, although both health- and insurance-related large donor and political action committee (PAC) contributions increased far faster than contributions by other industries. Contributions from health interests increased the fastest. The American Medical Association PAC was the leading contributor among health and insurance PACs. In the Senate, Republican incumbents received an average of 22.5 times as much from health and insurance interests as their Democratic challengers. No Democratic challenger was favored over an incumbent Republican. Democratic incumbents averaged only 3.5 times as much as their Republican challengers. Health and insurance interests favored seven of the nine Republicans seeking open Senate seats. Of course, one of the two Democrats favored was Jim Cooper, a leading opponent of comprehensive reform.