General morphology and axonal ultrastructure of the olfactory nerve of the pike, Esox lucius
- 1 July 1977
- journal article
- research article
- Published by Springer Nature in Cell and tissue research
- Vol. 181 (4), 443-457
- https://doi.org/10.1007/bf00221767
Abstract
The olfactory nerve of the European pike (Esox lucius) contains 5.1 × 106 axons with an average diameter of 0.20 ± 0,04 μm and a length of 5.5 cm in 1 meter long pike. Each axon contains an average of 4 microtubules as well as neurofilaments, smooth endoplasmic reticulum and about 500 mitochondria per centimeter. The number of neurofilaments ranges from zero in 15% of the cross sections to over 10 in 6%. Neurofilaments generally occur in clusters located opposite to microtubule regions. Smooth ER can not be identified in 14% of the cross sections suggesting that this structure may not be continuous. Microtubules often display annular regions (halos) of low electron density ranging in size from 800 to 1300 Å. Halos from adjacent tubules usually merge into regional halos. The ratio of axoplasm to glial cytoplasm is 4.4:1, while the ratio of axonal plasma membrane to glial plasma membrane exceeds 7:1. A 4 cm nerve contains 1280 cm2 of axolemma. This nerve represents an extreme in high density axonal packing and is therefore exceptionally well suited for biochemical, biophysical and physiological investigations.Keywords
This publication has 22 references indexed in Scilit:
- Rapid axoplasmic transport in the olfactory nerve of the pike: II. Analysis of transported proteins by SDS gel electrophoresisBrain Research, 1978
- Subcellular fractionation of rapidly transported axonal material in olfactory nerve: evidence for a size- dependent molecule separation during transportNeuroscience Letters, 1977
- The optical spikePflügers Archiv - European Journal of Physiology, 1976
- Neuronal fibrillar proteins and axoplasmic transportBrain Research, 1975
- Distribution along the axon and into various subcellular fractions of molecules labeled with [3H]leucine and rapidly transported in the garfish olfactory nerveBrain Research, 1975
- The microstream concept of axoplasmic and dendritic transport.1975
- Effekt von Zinkionen auf Struktur und Verteilung der NeurotubuliActa Neuropathologica, 1975
- The molecular organization of nerve membranes. VI. The separation of axolemma from Schwann cell membranes of giant and retinal squid axons by density gradient centrifugation.1972
- Microtubule-associated smooth endoplasmic reticulum in the frog's brainCell and tissue research, 1971
- OLFACTORY NERVE FIBERSThe Journal of general physiology, 1956