Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity
- 1 October 2001
- journal article
- Published by Elsevier in Journal of the Neurological Sciences
- Vol. 191 (1-2), 25-33
- https://doi.org/10.1016/s0022-510x(01)00627-x
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell deathAnnals of Neurology, 1999
- Metabolic Dysfunction in Familial, but Not Sporadic, Amyotrophic Lateral SclerosisJournal of Neurochemistry, 1998
- Massive Mitochondrial Degeneration in Motor Neurons Triggers the Onset of Amyotrophic Lateral Sclerosis in Mice Expressing a Mutant SOD1Journal of Neuroscience, 1998
- ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing InclusionsNeuron, 1997
- An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondriaNeuron, 1995
- Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS)Brain Research, 1995
- Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis.Proceedings of the National Academy of Sciences, 1995
- Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase MutationScience, 1994
- Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosisNature, 1993
- Progressive cytochrome c oxidase deficiency in a case of earns‐sayre syndrome: Morphological, immunological, and biochemical studies in muscle biopsies and autopsy tissuesAnnals of Neurology, 1987