MULTICENTRIC RETICULO-HISTIOCYTOSIS - REVIEW OF RECENT LITERATURE (SINCE 1969)

Abstract

The review of recent literature (since 1969) showed 35 human cases of multicentric reticulohistiocytosis. This entity was first described as a dermatological disease, then as a dermatoarthritis. It is a systemic disease which can involve many organs but is sometimes monosymptomatic. Its fatal outcome is sometimes the result of disseminated neoplasia or lymphoma. Its clinical and microscopic features allow one to distinguish it from solitary reticulohistiocytoma, generalized eruptive histiocytoma, congenital reticulohistiocytosis of Hashimoto and Pritzker and familial histiocytic dermatoarthritis of Zayid.