Nutritional Contribution of Volatile Fatty Acids from the Cecum of Rats

Abstract
The contribution of cecal acetic, propionic and butyric acids to rats' energy metabolism amounted to 4.7% of the caloric intake. This was determined by measuring rates of disappearance of these volatile fatty acids (VFA) from the cecum of rats killed at various intervals after the last meal. Further support indicating that VFA are energy sources for rats came from the appearance of 14CO2 in the breath when radioactive VFA were placed in their cecum.