IN VIVO TRANSMISSION OF DRUG RESISTANCE FACTORS BETWEEN STRAINS OF STAPHYLOCOCCUS AUREUS
Open Access
- 1 January 1967
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 125 (1), 45-59
- https://doi.org/10.1084/jem.125.1.45
Abstract
1. Multiply resistant strains of Staphylococcus aureus often harbor one or more extrachromosomal drug resistant factors as well as temperate prophages capable of mediating generalized transduction. 2. Spontaneous transduction occurs in mixed cultures of such staphylococcal strains, and the extrachromosomal resistance factors are involved more frequently than are chromosomal genes. 3. Spontaneous transduction of extrachromosomal determinants of erythromycin resistance and of linked penicillin-erythromycin resistance occurs in the kidneys of mice in which mixed infection has been induced.This publication has 10 references indexed in Scilit:
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- Transduction of Staphylococcus aureus to Tetracycline Resistance In VivoJournal of Bacteriology, 1965
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- Analysis by Transduction of Mutations affecting Penicillinase Formation in Staphylococcus aureusJournal of General Microbiology, 1963
- Bacteriophage Types in Penicillin-resistant Staphylococcal InfectionBMJ, 1949