• 1 January 1977
    • journal article
    • research article
    • Vol. 32 (6), 941-945
Abstract
EM findings made on microsomal fractions of rat liver after treatment with microsomal antibodies obtained from the blood of patients diagnosed as having chronic aggressive hepatitis and liver cirrhosis and after incubation with peroxidase-labeled antihuman Ig[immunoglobulin]G are described. Interpretation of these findings as the substrate of an antibody reaction directed against membranes of the endoplasmic reticulum of hepatocytes is discussed.