Potent Interaction Between Glucocorticoids and Growth Hormone-Releasing Factor in Vivo
- 5 August 1983
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 221 (4610), 556-558
- https://doi.org/10.1126/science.6408735
Abstract
Administration of dexamethasone significantly enhanced the pituitary growth hormone response to growth hormone-releasing factor in intact as well as adrenalectomized rats. Thus the inhibitory effects of glucocorticosteroids on somatic growth which involve an interaction of these steroids and growth hormone at a peripheral level may also involve a modification of pathways within the central nervous system that regulate normal growth hormone secretion.This publication has 30 references indexed in Scilit:
- A Noninvasive Functional Lesion of the Hypothalamo-Pituitary Axis for the Study of Growth Hormone-Releasing FactorNeuroendocrinology, 1983
- Growth Hormone-Releasing Factor from a Human Pancreatic Tumor That Caused AcromegalyScience, 1982
- Somatocrinin, growth hormone releasing factor, stimulates secretion of growth hormone in anesthetized ratsBiochemical and Biophysical Research Communications, 1982
- Regulated expression of human growth hormone genes in mouse cellsCell, 1982
- Corticosterone increases the synthesis of a soluble protein in pituitary glands from adrenalectomized male rats which precipitates with anti‐rat growth antiserumFEBS Letters, 1980
- Studies of the secretion and metabolic effects of human growth hormone in children with glucocorticoid-induced growth retardationThe Journal of Pediatrics, 1969
- Cortisol stimulation of growth hormone production by monkey adenohypophysis in tissue cultureBiochemical and Biophysical Research Communications, 1968
- Pituitary growth hormone suppression withlow-dosage, long-acting corticoid administrationThe Journal of Pediatrics, 1968
- A FUNDAMENTAL DEFECT OF ADRENOCORTICAL CONTROL IN CUSHING'S DISEASEJournal of Endocrinology, 1968
- A comparison of the growth suppressive effect of cortisone, prednisone, and other adrenal cortical hormonesJournal of Allergy, 1960