Transdifferentiation in Animal Cells: Fact or Artifact?
- 1 May 1986
- journal article
- review article
- Published by Wiley in Development, Growth & Differentiation
- Vol. 28 (3), 213-221
- https://doi.org/10.1111/j.1440-169x.1986.00213.x
Abstract
Some specialized animal cells can overtly change from one differentiated phenotype to another through the process of transdifferentiation. In this review article, representative and convincing examples of transdifferentiation in cells of various animals ranging from mammals to coelenterates are presented. Several basic nature of the cellular properties that underly the transdifferentiation process is discussed. Studies are in progress to understand the mechanism of transdifferentiation in terms of gene expression.Keywords
This publication has 40 references indexed in Scilit:
- Clonal sublines of rat neurotumor RT4 and cell differentiationDevelopmental Biology, 1985
- Recent progress in studies of the transdifferentiation of eye tissue in vitroCell Differentiation, 1983
- Lentoids in aggregates of embryonic neural retina cellsCell Differentiation, 1981
- Relationship between crystallin mRNA expression in retina cells and their capacity to re-differentiate into lens cellsNature, 1979
- Possible demonstration of multipotential nature of embryonic neural retina by clonal cell cultureDevelopmental Biology, 1979
- Sequence complexity and tissue distribution of chick lens crystallin mRNAsDevelopmental Biology, 1978
- Formation of cartilage by non-chondrogenic cell typesDevelopmental Biology, 1978
- Differentiation of lens in cultures of neural retinal cells of chick embryosDevelopmental Biology, 1975
- Proliferation of amphibian melanophores in vitroDevelopmental Biology, 1974
- Transdifferentiation in the labial gland of silk moths: is DNA required for cellular metamorphosis?Cell Differentiation, 1974