A Double-blind Crossover Trial of Baclofen-a New Treatment for the Unstable Bladder Syndrome

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Abstract
Forty patients with the unstable bladder syndrome have been treated in a double-blind crossover trial of baclofen 5 mg qds versus placebo. Baclofen significantly improved diurnal and nocturnal frequency of micturition and the severity of incontinence. Considerable improvement was also obtained with placebo.