Peptide Synthesis by Oxidation-Reduction Condensation. II. The Use of Disulfide as an Oxidant
- 1 May 1971
- journal article
- research article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 44 (5), 1373-1378
- https://doi.org/10.1246/bcsj.44.1373
Abstract
A peptide synthesis starting from free N-protected amino acid and free amino acid ester by the use of triphenylphosphine, an oxygen acceptor, and disulfide, a hydrogen acceptor, was studied. The oxidation-reduction condensation reaction affords peptides with high optical purity in excellent yields by simple procedure.Keywords
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