The Measurement of Total and Unsaturated Iron‐Binding Capacity in Serum

Abstract

An inter-laboratory investigation into the assay of serum iron binding capacity by the magnesium carbonate adsorption method was undertaken. The source of MgCO₃, storage temperature of whole serum, lyophilization and storage temperature of lyophilized serum were identified as sources of inter-laboratory variation. Protocols for the clinical assay of UIBC and TIBC are given which have achieved satisfactory inter-laboratory precision.