G‐protein‐coupled receptors: past, present and future
- 1 January 2006
- journal article
- review article
- Published by Wiley in British Journal of Pharmacology
- Vol. 147 (S1), S27-S37
- https://doi.org/10.1038/sj.bjp.0706455
Abstract
The G-protein-coupled receptor (GPCR) family represents the largest and most versatile group of cell surface receptors. Drugs active at these receptors have therapeutic actions across a wide range of human diseases ranging from allergic rhinitis to pain, hypertension and schizophrenia. This review provides a brief historical overview of the properties and signalling characteristics of this important family of receptors.Keywords
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