The ‘cyclization’ of vitamin A and allied compounds

Abstract
[beta]-Apo-2-carotenal, axeroph-thylideneacetone, and the C20 aldehyde obtained by oxidation of vit.-A alcohol fail to undergo "cyclization" on treatment with alcoholic HC1, whereas axerophthylideneiso-propyl alcohol gives a compound which shows the characteristic fine structure of a "cyclized" product. The bearing of these and other observations on the structure of "cyclized" vit.-A, vit.-A2, and subvit.-A is discussed.

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