SKIN REACTIONS TO NUCLEOPROTEIN OF STREPTOCOCCUS SCARLATINAE IN PATIENTS WITH RHEUMATOID ARTHRITIS AND RHEUMATIC FEVER
Open Access
- 1 March 1933
- journal article
- research article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 12 (2), 279-289
- https://doi.org/10.1172/jci100502
Abstract
Acute rheumatic fever and rheumatoid arthritis (59 cases) gave 70% of positive skin reactions to the nucleoprotein of a strain of Strep. scarlatinae. Of 207 controls without rheumatic fever or rheumatoid arthritis, 44%, and of 20 patients with respiratory infection, associated with hemolytic streptococci, 95% showed positive reactions. There was no correlation between positive skin tests and presence of agglutinins in the blood serum. The positive skin reaction was regarded as an evidence of allergy to the nucleoprotein of the hemolytic streptococcus.This publication has 5 references indexed in Scilit:
- SKIN REACTIONS OF PATIENTS AND NORMAL INDIVIDUALS TO PROTEIN EXTRACTS OF STREPTOCOCCI 1JCI Insight, 1931
- SKIN REACTIONS TO FILTRATES OF HAEMOLYTIC STREPTOCOCCI IN ACUTE AND SUBACUTE NEPHRITIS 1JCI Insight, 1929
- Skin Reactions in Rheumatic Fever (Birkhaug Test): Studies in 801 Persons with the Toxic Filtrate Produced by the Non-Methemoglobin-Forming Streptococcus Isolated from Cases of Rheumatic FeverThe Journal of Infectious Diseases, 1928
- FURTHER STUDIES ON BACTERIAL ALLERGY THE ANTIGEN INVOLVED IN PNEUMOCOCCUS ALLERGYJournal of Bacteriology, 1927