Therapeutic Factors in Survival after Lethal Cholinesterase Inhibition by Phosphorus Insecticides

Abstract

THE purpose of this paper is to acquaint the clinician with the intoxication produced by some of the commonly used phosphate insecticides, the material being based on a survey of the severe and fatal cases that have occurred since their use was introduced several years ago.Accidental poisoning with organic phosphoric acid esters has been of profound interest in these laboratories since it was learned in 1946 that the Germans had adapted such compounds to military use in the form of highly toxic, volatile and almost odorless nerve gases. Similarities in biologic effects and chemical structure between these insecticides and . . .