Vasopressin Analogs That Antagonize Antidiuretic Responses by Rats to the Antidiuretic Hormone

Abstract
Four new synthetic analogs of vasopressin (antidiuretic hormone) can antagonize the antidiuretic response to intravenous vasopressin in anesthetized, water-loaded rats. They also cause a diuresis resembling that of diabetes insipidus when given intraperitoneally to conscious rats. Such antagonists may prove to be useful both pharmacologically and therapeutically.

This publication has 25 references indexed in Scilit: