Recognition of Cancer in vivo by Nuclear Magnetic Resonance

Abstract

Pulsed nuclear magnetic resonance has been used to differentiate in vivo between normal mouse tail tissue and a malignant transplanted melanoma, S91, located on the tail. The tumor displayed a nuclear (proton) spin-lattice relaxation time of ∼0.7 second contrasted with the simultaneously measured normal tail tissue relaxation time of ∼0.3 second.