Mutations in the Glucocerebrosidase Gene and Parkinson's Disease in Ashkenazi Jews
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Open Access
- 4 November 2004
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 351 (19), 1972-1977
- https://doi.org/10.1056/nejmoa033277
Abstract
A clinical association has been reported between type 1 Gaucher's disease, which is caused by a glucocerebrosidase deficiency owing to mutations in the glucocerebrosidase gene (GBA), and parkinsonism. We examined whether mutations in the GBA gene are relevant to idiopathic Parkinson's disease.Keywords
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