THE INFLUENCE OF ACTH, CORTISONE, AND HYDROCORTISONE ON THE DISTRIBUTION AND PERIPHERAL METABOLISM OF THYROXINE 1

Abstract
Influence of cortisone, hydrocortisone, and ACTH on the distribution and rate of turnover of radioactive thyroxine was studied in 8 patients with treated myxedema and 2 patients with panhypopituitarism. As judged by the metabolism of radioactive thyroxine and by measurements of serum precipitable I, ACTH and cortical steroids did not alter the rate of degradation of thyroxine.