Poliomyelitis Virus in Human Blood During the "Minor Illness" and the Asymptomatic Infection.

Abstract

Poliomyelitis virus was isolated from the blood of 4 children in one family during a poliomyelitis epidemic in Ohio in 1952. Three of the children had characteristic clinical pictures of the minor illness or abortive poliomyelitis, and one was asymptomatic. All were found to have virus in the throat and rectal swabs as well as in the blood. None went on to develop signs or symptoms of the major illness, either paralytic or non-paralytic. All strains of virus isolated proved to belong to Type I as demonstrated by tissue culture neutralization tests.