The Sequence Alignment/Map format and SAMtools
Top Cited Papers
Open Access
- 8 June 2009
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 25 (16), 2078-2079
- https://doi.org/10.1093/bioinformatics/btp352
Abstract
Summary: The Sequence Alignment/Map (SAM) format is a generic alignment format for storing read alignments against reference sequences, supporting short and long reads (up to 128 Mbp) produced by different sequencing platforms. It is flexible in style, compact in size, efficient in random access and is the format in which alignments from the 1000 Genomes Project are released. SAMtools implements various utilities for post-processing alignments in the SAM format, such as indexing, variant caller and alignment viewer, and thus provides universal tools for processing read alignments. Availability:http://samtools.sourceforge.net Contact:rd@sanger.ac.ukKeywords
This publication has 4 references indexed in Scilit:
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeGenome Biology, 2009
- Next-Generation DNA Sequencing MethodsAnnual Review of Genomics and Human Genetics, 2008
- Mapping short DNA sequencing reads and calling variants using mapping quality scoresGenome Research, 2008
- The Human Genome Browser at UCSCGenome Research, 2002