Effect of simvastatin (MK-733) on the regulation of cholesterol synthesis in Hep G2 cells
- 31 July 1990
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 40 (4), 843-850
- https://doi.org/10.1016/0006-2952(90)90325-f
Abstract
No abstract availableThis publication has 50 references indexed in Scilit:
- Preventive effect of MK-733 (simvastatin), an inhibitor of HMG-CoA reductase, on hypercholesterolemia and atherosclerosis induced by cholesterol feeding in rabbits.The Japanese Journal of Pharmacology, 1989
- Lipid and lipoprotein metabolism in Hep G2 cellsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1988
- EFFECTS OF SYNVINOLIN (MK-733) ON PLASMA LIPIDS IN FAMILIAL HYPERCHOLESTEROLAEMIAThe Lancet, 1986
- CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal speciesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1986
- 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 4. Side-chain ester derivatives of mevinolinJournal of Medicinal Chemistry, 1986
- A Receptor-Mediated Pathway for Cholesterol HomeostasisScience, 1986
- Primary Hepatocytes in Monolayer Culture: A Model for Studies on Lipoprotein MetabolismAnnual Review of Physiology, 1984
- Effects of compactin, mevalonate and low-density lipoprotein on 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and low-density-lipoprotein-receptor activity in the human hepatoma cell line Hep G2Biochemical Journal, 1984
- The metabolism in vitro of human low-density lipoprotein by the human hepatoma cell line Hep G2Biochemical Journal, 1983
- Competitive inhibition of 3‐hydroxy‐3‐methylglutaryl coenzyme a reductase by ML‐236A and ML‐236B fungal metabolites, having hypocholesterolemic activityFEBS Letters, 1976