Abnormalities of the peripheral circulation and respiratory function in patients with severe heart failure.
Open Access
- 1 January 1986
- Vol. 55 (1), 75-80
- https://doi.org/10.1136/hrt.55.1.75
Abstract
To investigate the peripheral circulatory and respiratory abnormalities which occur in patients with heart failure, forearm and calf blood flow were measured before and after upright exercise, and respiratory gas exchange was measured during exercise in 26 patients with severe heart failure. Compared with a group of normal subjects the patients had reduced limb blood flow at rest and the response of limb blood flow to upright exercise was also abnormal. The increase in calf blood flow after exercise and the reduction in blood flow in the non-exercising forearm were both smaller in patients than in controls. There was a significant correlation between the maximum exercise duration of the patients and calf blood flow both after exercise and at rest. Compared with another group of control subjects the patients had a higher minute ventilation during exercise and a reduced oxygen consumption. The respiratory exchange ratio during exercise was also higher in patients than in controls. This suggests that there is early onset of anaerobic metabolism during exercise in patients with severe heart failure.This publication has 18 references indexed in Scilit:
- Lack of correlation between exercise capacity and indexes of resting left ventricular performance in heart failureThe American Journal of Cardiology, 1981
- HAEMODYNAMIC, HORMONAL, AND ELECTROLYTE RESPONSES TO CAPTOPRIL IN RESISTANT HEART FAILUREThe Lancet, 1980
- Metabolic assessment of exercise in chronic heart failure patients treated with short-term vasodilators.Circulation, 1980
- Functional capacity of patients with chronic left ventricular failureAmerican Journal Of Medicine, 1979
- Hydralazine in the management of left ventricular failureThe American Journal of Cardiology, 1979
- Hemodynamic assessment of oral peripheral vasodilator therapy in chronic congestive heart failure: Prolonged effectiveness of isosorbide dinitrateThe American Journal of Cardiology, 1977
- Cardiocirculatory responses to muscular exercise in congestive heart failureProgress in Cardiovascular Diseases, 1977
- Impaired forearm oxygen consumption during static exercise in patients with congestive heart failure.Circulation, 1976
- Treadmill exercise in assessment of the functional capacity of patients with cardiac diseaseThe American Journal of Cardiology, 1972
- METHODS FOR THE INVESTIGATION OF PERIPHERAL BLOOD FLOWBritish Medical Bulletin, 1963