Molecular Basis of Drug Recognition by Specific T–Cell Receptors
- 1 July 1999
- journal article
- review article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 119 (3), 173-180
- https://doi.org/10.1159/000024192
Abstract
In recent years the involvement of T cells in allergic reactions to drugs has been well established. However, several molecular aspects of drug recognition by specific T cells remain still unclear. This review will discuss the known pathways of drug presentations by antigen presenting cells, the recognition of MHC/peptide/drug complexes by specific T–cell receptors, and the activation mechanism of drug–specific T cells.Keywords
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