Clinical Relevance of MGMT in the Treatment of Cancer
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- 1 May 2002
- journal article
- review article
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 20 (9), 2388-2399
- https://doi.org/10.1200/jco.2002.06.110
Abstract
A number of DNA-damaging chemotherapeutic agents attack the O6 position on guanine, forming the most potent cytotoxic DNA adducts known. The DNA repair enzyme O6-alkylguanine DNA alkyltra...Keywords
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