Effect of Sodium N-Palmitoyl Sarcosinate on Tooth Enamel Solubility

Abstract

Of the N-acyl derivatives of sodium sarcosine studied, sodium N-lauroyl sarcosinate produced the least effect and sodium N-palmitoyl sarcosinate produced the greatest effect in reducing the acid solubility of powdered human enamel. Aqueous solutions of 1%, 0.5%, 0.1% and 0.01% of sodium N-palmitoyl sarcosinate were shown to reduce the solubility of powdered human enamel to a degree comparable to that observed with sodium fluoride solutions. These observations may be of importance in the prevention of dental caries.