Isolation of an Antibiotic Agent Derived from a Phycomyces Active in vitro Against Trypanosoma eguiperdum.

Abstract

Certain soil fungi have the capacity of forming substances active against T. equiperdum. From a Phycomyces sp., a lipid-like substance was isolated which immobilized the trypanosome in vitro but exerted no protective action against the exptl. infection in mice.