RNA-dependent DNA polymerase activity of RNA tumor virus. VI. Processive mode of action of avian myeloblastosis virus polymerase
- 1 September 1976
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 19 (3), 932-939
- https://doi.org/10.1128/jvi.19.3.932-939.1976
Abstract
Purified avian myeloblastosis virus (AMV) polymerase consisting of .alpha.,.beta. subunits acted processively in catalyzing DNA synthesis primed with 34S AMV RNA.cntdot.oligo(dT), poly(A).cntdot.poly(dT) and poly(I).cntdot.poly(dC). DNA transcripts prepared with 34S AMV RNA.cntdot.oligo(dT)14 and AMV polymerase (.alpha..beta.) had a MW of 1.05 .times. 106, or approximately 1/3 the size of the 34S RNA genome. Polymerase subunit .alpha. acts nonprocessively with the above templates.This publication has 31 references indexed in Scilit:
- Characterization of reverse transcriptase and RNase H from friend-murine leukemia virusVirology, 1974
- Reverse Transcriptase and RNase H: Present in a Murine Virus and in Both Subunits of an Avian VirusCold Spring Harbor Symposia on Quantitative Biology, 1974
- A Single Subunit from Avian Myeloblastosis Virus with Both RNA-Directed DNA Polymerase and Ribonuclease H ActivityProceedings of the National Academy of Sciences, 1973
- A DNA-Unwinding Protein Isolated from Escherichia coli: Its Interaction with DNA and with DNA PolymerasesProceedings of the National Academy of Sciences, 1972
- Degradation of DNA RNA Hybrids by Ribonuclease H and DNA Polymerases of Cellular and Viral OriginProceedings of the National Academy of Sciences, 1972
- Ribonucleic acid directed deoxyribonucleic acid synthesis by the purified deoxyribonucleic acid polymerase of Rous sarcoma virus. Characterization of the enzymic productBiochemistry, 1972
- Comparative Properties of RNA and DNA Templates for the DNA Polymerase of Rous Sarcoma VirusProceedings of the National Academy of Sciences, 1971
- Purification of the DNA polymerase of avian myeloblastosis virusBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1971
- T4 Bacteriophage Gene 32: A Structural Protein in the Replication and Recombination of DNANature, 1970
- Sedimentation studies of the size and shape of DNAJournal of Molecular Biology, 1965