Rapid Purification of Lymphocytic Choriomeningitis Virus by Density Gradient Centrifugation in Colloidal Silica

1 January 1979

journal article
Published by Microbiology Society in Journal of General Virology

Vol. 42 (1), 215-218
https://doi.org/10.1099/0022-1317-42-1-215

Abstract

Lymphocytic choriomeningitis virus was purified from cell culture fluid by density gradient centrifugation in colloidal silica. The specific infectivity increased 5000-fold and the recovery of infectivity was about 10%.

Keywords

CELL CULTURE
CULTURE FLUID
LYMPHOCYTIC CHORIOMENINGITIS
CHORIOMENINGITIS VIRUS
SPECIFIC INFECTIVITY
SILICA LYMPHOCYTIC
INFECTIVITY INCREASED

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