OBSTRUCT: a program to obtain largest cliques from a protein sequence set according to structural resolution and sequence similarity

Abstract

A program OBSTRUCT has been developed to obtain the largest possible subset according to specific constraints from a set of protein sequences whose tertiary structures have been determined crystallographically. The user can request a range in sequence similarity level and/or structural resolution. The program optionally includes sequences with known three–dimensional folds elicited from NMR data.