Characterization of a polypeptide from human seminal plasma with inhibin (inhibition of FSH secretion)‐like activity
- 2 January 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 165 (1), 11-15
- https://doi.org/10.1016/0014-5793(84)80004-6
Abstract
A polypeptide in preparations of ‘large’ form (Mr ∼14 000) material with inhibin-like activity (inhibiting FSH secretion) has been isolated from human seminal plasma. Its amino acid composition, cleavage pattern with CNBr, N-terminal sequence, and properties on reverse-phase high-performance liquid chromatography establish this inhibin-like preparation to be homogeneous. The polypeptide contains close to 130 residues, has a free N-terminal serine residue, a methionine residue in position 19, and a dibasic structure (Arg—Lys) in positions 16–17Keywords
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