Mechanism of regulation of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor protein
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- 15 August 2000
- journal article
- Published by Springer Nature in The EMBO Journal
- Vol. 19 (16), 4298-4309
- https://doi.org/10.1093/emboj/19.16.4298
Abstract
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.Keywords
This publication has 29 references indexed in Scilit:
- Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complexProceedings of the National Academy of Sciences, 1999
- Substrate Targeting in the Ubiquitin SystemCell, 1999
- Transactivation and Inhibitory Domains of Hypoxia-inducible Factor 1αJournal of Biological Chemistry, 1997
- Activation of hypoxia-inducible factor 1α: Posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factorProceedings of the National Academy of Sciences, 1997
- Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α SubunitJournal of Biological Chemistry, 1997
- An essential role for p300/CBP in the cellular response to hypoxiaProceedings of the National Academy of Sciences, 1996
- Functional Interference between Hypoxia and Dioxin Signal Transduction Pathways: Competition for Recruitment of the Arnt Transcription FactorMolecular and Cellular Biology, 1996
- Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.Proceedings of the National Academy of Sciences, 1996
- Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene.Proceedings of the National Academy of Sciences, 1996
- Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.Proceedings of the National Academy of Sciences, 1995