Proteolytic degradation of protamine during thiol-induced nuclear decondensation in rabbit spermatozoa
- 1 May 1978
- journal article
- research article
- Published by Wiley in Journal of Experimental Zoology
- Vol. 204 (2), 283-289
- https://doi.org/10.1002/jez.1402040216
Abstract
Rabbit sperm nuclei decondensed when incubated with dithiothreitol and Triton X-100. Protamine isolated from these nuclei during the course of treatment exhibited marked and progressive degradation. Timed interval experiments revealed that the degradation of protamine significantly preceded sperm nuclear decondensation and reached its maximum extent before decondensation was completed. Studies with protease inhibitors demonstrated that proteolysis was involved in both nuclear decondensation and protamine degradation.This publication has 10 references indexed in Scilit:
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