Differential Mood Changes Following Basal Ganglia vs Thalamic Lesions
- 1 July 1988
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 45 (7), 725-730
- https://doi.org/10.1001/archneur.1988.00520310031013
Abstract
• Patients with computed tomographic scan-verified unilateral lesions in the basal ganglia or thalamus were examined for the presence of poststroke mood disorders. Patients with left-sided basal ganglia lesions (mainly in the head of the caudate nucleus) showed a significantly higher frequency and severity of depression, as compared with patients with right-sided basal ganglia or thalamic (leftor right-sided) lesions. Results suggest that damage to biogenic amine pathways and/or frontocaudate projections may play an important role in the modulation of mood.This publication has 33 references indexed in Scilit:
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