Freezing as a Path to Build Complex Composites
Top Cited Papers
- 27 January 2006
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 311 (5760), 515-518
- https://doi.org/10.1126/science.1120937
Abstract
Materials that are strong, ultralightweight, and tough are in demand for a range of applications, requiring architectures and components carefully designed from the micrometer down to the nanometer scale. Nacre, a structure found in many molluscan shells, and bone are frequently used as examples for how nature achieves this through hybrid organic-inorganic composites. Unfortunately, it has proven extremely difficult to transcribe nacre-like clever designs into synthetic materials, partly because their intricate structures need to be replicated at several length scales. We demonstrate how the physics of ice formation can be used to develop sophisticated porous and layered-hybrid materials, including artificial bone, ceramic-metal composites, and porous scaffolds for osseous tissue regeneration with strengths up to four times higher than those of materials currently used for implantation.Keywords
This publication has 27 references indexed in Scilit:
- Rigid Biological Systems as Models for Synthetic CompositesScience, 2005
- Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fractureNature Materials, 2005
- Performance of degradable composite bone repair products made via three‐dimensional fabrication techniquesJournal of Biomedical Materials Research Part A, 2003
- A new method to produce macropores in calcium phosphate cementsBiomaterials, 2002
- Third-Generation Biomedical MaterialsScience, 2002
- Freeze Casting of Aqueous Alumina Slurries with GlycerolJournal of the American Ceramic Society, 2001
- Controlling Cracks in CeramicsScience, 1999
- Cellular biocompatibility and resistance to compression of macroporous β-tricalcium phosphate ceramicsBiomaterials, 1998
- Natural Convection, Solute Trapping, and Channel Formation during Solidification of SaltwaterThe Journal of Physical Chemistry B, 1997
- Influence of porosity and pore size on the compressive strength of porous hydroxyapatite ceramicCeramics International, 1997