Secoverine hydrochloride is a muscarinic antagonist in human isolated gastrointestinal muscle and myometrium
- 1 September 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 33 (1), 711-714
- https://doi.org/10.1111/j.2042-7158.1981.tb13910.x
Abstract
Secoverine is a new antimuscarinic agent thought to be selective for smooth muscle. We have found it to be a potent anticholinergic antagonist of acetylcholine in strips of human gastrointestinal and uterine muscle. The pA2 values in gut longitudinal and circular muscle and myometrium were 9·1, 9·3 and 8·6 respectively.This publication has 11 references indexed in Scilit:
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