SOME EFFECTS OF INCREASED FOOD CONSUMPTION ON THE COMPOSITION OF CARCASS AND LIVER OF HYPOPHYSECTOMIZED RATS

Abstract

Hypophysectomized adult rats, forcibly fed quantities of food approx. isocaloric with those consumed by normal rats, gained instead of losing wt. Carcass analyses show that the large losses of protein and water occurring after removal of the pituitary were nearly completely prevented by increased food intake. The gain in wt. was due entirely to excessive fat deposition. Post-hypophysectomy changes in wt. and composition of the liver were also nearly completely prevented but the weight losses of kidneys, testes and adrenal glands were not affected by the increased food intake.