Ophthalmic Manifestations of Subacute Sclerosing Panencephalitis
- 1 April 1970
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 83 (4), 426-435
- https://doi.org/10.1001/archopht.1970.00990030426007
Abstract
Case histories of eight patients with subacute sclerosing panencephalitis are presented, with emphasis on ocular manifestations of the disease. This illness, familiar to European ophthalmologists, is previously unreported in the American ophthalmic literature. Focal chorioretinitis was present in four of the eight patients and was the most striking ocular manifestation. Nystagmus, cortical blindness, papilledema, and optic atrophy were also present in some patients. There is evidence that a myxovirus, probably that of rubeola, is the etiologic agent of this encephalitis; serologic and other tests to identify other etiologies for the chorioretinitis were negative except for possibly coincidental toxoplasmic infections in two patients. Further clarification of the retinal lesions awaits histopathologic study of affected eyes.Keywords
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