Distribution of intact and Fab1 2 fragments of anti-human chorionic gonadotrophin antibodies in nude mice bearing human choriocarcinoma xenografts
- 1 April 1986
- journal article
- conference paper
- Published by Springer Nature in Cancer Immunology, Immunotherapy
- Vol. 21 (3), 205-208
- https://doi.org/10.1007/bf00199363
Abstract
A direct comparative study of the distribution of intact and Fab1 2 fragments of mouse monoclonal anti-human chorionic gonadotrophin antibody, W14A, in nude mice bearing a human choriocarcinoma xenograft, indicates that the tumour:blood ratio is generally improved with fragments. Some parameters which may determine the distribution are outlined.Keywords
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