Protective Effect of Adrenal Steroid Administration on Irradiated Mice
- 1 November 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 81 (2), 397-400
- https://doi.org/10.3181/00379727-81-19888
Abstract
Young male and female DBA mice were exposed to 500 r head radiation or whole-body radiation. A correlation was observed between head and whole-body radiation as judged by the mortality rates. In both instances a 500 r dose gave a 100% mortality rate, but mice receiving whole-body radiation succumbed sooner. Mice receiving 500 r head radiation and treated before or after radiation with cortisone or desoxycorticosterone showed evidence that both of these compounds afford protection from the lethal effect of ionizing radiation.Keywords
This publication has 6 references indexed in Scilit:
- EVIDENCE FOR A HUMORAL FACTOR (OR FACTORS) CONCERNED IN RECOVERY FROM RADIATION INJURY - A REVIEW1952
- THE INFLUENCE OF ADRENAL CORTICAL HORMONES ON SENSITIVITY OF MICE TO IONIZING RADIATION1Endocrinology, 1950
- Pharmacological Modification of Resistance to Radiation—A Preliminary-ReportProceedings of the National Academy of Sciences, 1949
- ADRENAL RESPONSE TO TOTAL BODY X-RADIATIONAmerican Journal of Physiology-Legacy Content, 1947
- Some Effects of Desoxycorticosterone Acetate on Mice Irradiated with X-rays.Experimental Biology and Medicine, 1947
- EFFECT OF COMBINING ESTROGEN WITH LETHAL DOSES OF ROENTGEN-RAY IN SWISS MICE1Endocrinology, 1943