THE sulfonamides have become well established as invaluable agents in the treatment of many infective conditions. As a result, the tendency has been to regard the drugs equally effective in any infective state, and they are given routinely by many physicians whenever a febrile inflammatory condition develops.For some time, we had doubted the value of the sulfonamides in many of the cases of pelvic inflammatory disease under our care at the Metropolitan Hospital. We therefore examined the literature to determine the experience of others in the use of the drugs in such diseases.As early as 1938, Gillett1 believed . . .