INSULIN STIMULATION TESTS IN PITUITARY DEPENDENT CUSHING'S SYNDROME AFTER COMPLETE ADRENALECTOMY
- 1 November 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 86 (3), 578-582
- https://doi.org/10.1530/acta.0.0860578
Abstract
In a group of 6 euadrenal patients, previously treated by complete adrenalectomy for pituitary dependent Cushing''s syndrome, the stress stimulus of insulin-induced hypoglycemia is followed by a plasma ACTH response which is of similar magnitude as the response obtained with lysine-vasopressin. The CNS-pituitary axis is basically normal in pituitary dependent Cushing''s syndrome as assessed by insulin induced hypoglycemia. Non-responsiveness of the pituitary-adrenocortical system to insulin-induced hypoglycemia in untreated patients with pituitary dependent Cushing''s syndrome does not represent a fundamental defect of the stress mechanism, but is due to hypercorticism per se.This publication has 7 references indexed in Scilit:
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