Amidino substituted 2-aminophenols: biologically important building blocks for the amidino-functionalization of 2-substituted benzoxazoles
- 2 March 2021
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic & Biomolecular Chemistry
- Vol. 19 (12), 2784-2793
- https://doi.org/10.1039/d1ob00235j
Abstract
A new synthetic strategy involving the Pinner reaction offers various amidino-functionalized 2-substituted benzoxazolesviaamidino-substituted 2-aminophenols with sub-micromolar antiproliferative activities.Funding Information
- Hrvatska Zaklada za Znanost (HRZZ-IP-2018-01-4379)
This publication has 35 references indexed in Scilit:
- Designed Compounds for Recognition of 10 Base Pairs of DNA with Two AT Binding SitesJournal of the American Chemical Society, 2012
- Synthesis, anti-inflammatory, and anticancer activity evaluation of some heterocyclic amidine and bis-amidine derivativesJournal of Heterocyclic Chemistry, 2011
- Novel Diamidino-Substituted Derivatives of Phenyl Benzothiazolyl and Dibenzothiazolyl Furans and Thiophenes: Synthesis, Antiproliferative and DNA Binding PropertiesJournal of Medicinal Chemistry, 2010
- Novel amidino substituted 2-phenylbenzothiazoles: Synthesis, antitumor evaluation in vitro and acute toxicity testing in vivoBioorganic & Medicinal Chemistry, 2010
- Preparation and Utility of Trihaloethyl Imidates: Useful Reagents for the Synthesis of AmidinesThe Journal of Organic Chemistry, 2010
- Design of DNA Minor Groove Binding Diamidines That Recognize GC Base Pair Sequences: A Dimeric-Hinge Interaction MotifJournal of the American Chemical Society, 2007
- Mechanism of Polyphosphoric Acid and Phosphorus Pentoxide−Methanesulfonic Acid as Synthetic Reagents for Benzoxazole FormationThe Journal of Organic Chemistry, 1997
- Facile Rearrangements of Alkynylamino Heterocycles with Noble Metal CationsThe Journal of Organic Chemistry, 1996
- PREPARATION OF AN o-SUBSTITUTED BENZAMIDINE BY THE PINNER METHOD. A LITERATURE CLARIFICATIONOrganic Preparations and Procedures International, 1990
- 653. Some potential trypanocidal and antibacterial compounds in the heterocyclic series. Part IIJournal of the Chemical Society, 1950