Interaction of Mg2+ions with nucleoside triphosphates by phosphorus magnetic resonance spectroscopy
Open Access
- 1 January 1975
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 2 (7), 1101-1110
- https://doi.org/10.1093/nar/2.7.1101
Abstract
The interaction of Mg2+ with nucleoside triphosphates: ATP, GTP, CTP and UTP has been studied by phosphorus Magnetic resonance spectroscopy in aqueous solution. The results show that these four nucleotides behave similarly. Purine and Purimidine bases have almost no effect on the phosphate groups even in the N7 pK region of ATP and GTP. The Mg2+ ion binds not to the α and β phosphate group. The fixation is stronger at neutral pH than at acid pH.Keywords
This publication has 15 references indexed in Scilit:
- Fourier transform phosphorus magnetic resonance study of ATP -- calcium -- G-actin complexBiochemical and Biophysical Research Communications, 1974
- Carbon-13 relaxation studies on the manganese(II)-adenosine 5'-triphosphate complex in solutionJournal of the American Chemical Society, 1974
- Measurement of the water exchange rate of bound water in the manganese(II)-adenosine triphosphate complex by oxygen-17 nuclear magnetic resonanceBiochemistry, 1973
- NUCLEOTIDE SPECIFICITY AND CONFORMATION OF ACTIVE SITE OF CREATINE KINASE - MAGNETIC RESONANCE AND SULFHYDRYL REACTIVITY STUDIES1966
- Nuclear Magnetic Resonance Study of Metal-Ion Binding to Adenosine Triphosphate. II. Proton StudiesThe Journal of Chemical Physics, 1965
- Nuclear Magnetic Resonance Study of Metal-Ion Binding to Adenosine Triphosphate. I. 31P StudiesThe Journal of Chemical Physics, 1965
- Magnetic Resonance Studies of Metal Activation of Enzymic Reactions of Nucleotides and Other Phosphate Substrates*Biochemistry, 1963
- NUCLEAR MAGNETIC RESONANCE SPECTRA OF ADENOSINE DI- AND TRIPHOSPHATE .2. EFFECT OF COMPLEXING WITH DIVALENT METAL IONS1962
- MECHANISM OF ENZYME ACTIONAnnual Review of Biochemistry, 1960
- Bond cleavage in enzymic hydrolysis of nucleoside triphosphate to nucleoside monophosphate and inorganic pyrophosphateBiochimica et Biophysica Acta, 1960