γ-Irradiation of Pneumococcus Deoxyribonucleic Acid
- 1 October 1955
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 3 (2), 116-120
- https://doi.org/10.2307/3570303
Abstract
Alterations in the transforming activity of deoxyribonucleic acid (DNA) from Diplococcus pneumoniae, type III, subsequent to gamma-irradiation were investigated. When DNA is irradiated in saline, doses of the order of 10,000 to 20,000 rep result in a significant decrease in transforming activity; complete inactivation is achieved at 40,000 rep. Much greater intensities are required to inactivate DNA irradiated in 0.5% cysteine solution. Transforming activity was demonstrated in DNA preparations exposed to 250,000 rep. Highly active transforming principle was isolated from cells exposed to radiation doses that have a marked effect on cell survival.This publication has 4 references indexed in Scilit:
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- X-Ray-induced Depolymerization of Thymonucleohistone and of Sodium ThymonucleateScience, 1946
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